The reality television show that defined the genre is back for the first time in five years - and the Big Brother house has now welcomed its latest residents.
First broadcast on Channel 4 in 2000 - when millions were glued to the antics of Nasty Nick, Craig Phillips and Anna Nolan - the prorgamme later moved to Channel 5 before being cancelled in 2018.
Now it's been relaunched on ITV2, with a second series already confirmed.
Here's who the bookies think has the best - and worst - chance of becoming the latest entry in the Big Brother hall of fame.
5. Jenkin
The bookies are offering odds of 10/1 on 25-year-old Bridgend barman Jenkin triumphing. | ITV
7. Chanelle
Dental therapits Chanelle is from Llanelli. The dental therapist is 12/1 to be last to be evicted. | ITV
8. Kerry
The second of four housemates priced at 12/1 is Kerry, a 40-year-old NHS manager from Essex. | ITV