The reality television show that defined the genre is back for the first time in five years - and the Big Brother house has now welcomed its latest residents.
First broadcast on Channel 4 in 2000 - when millions were glued to the antics of Nasty Nick, Craig Phillips and Anna Nolan - the prorgamme later moved to Channel 5 before being cancelled in 2018.
Now it's been relaunched on ITV2, with a second series already confirmed.
Here's who the bookies think has the best - and worst - chance of becoming the latest entry in the Big Brother hall of fame.
13. Henry
25-year old Costswolds food writer Henry is 16/1 to avoid the boot until the end. | ITV
14. Matty
Joining Henry at 16/1 is Matty, a 24-year-old doctor from the Isle of Man. | ITV
15. Farida
Long-shot Farida, a 50-year-old make-up artist from Wolverhampton, is a lengthy 25/1 for the reality television crown. | ITV
16. Noky
The other outsider is banker and former Miss Universe Great Britain Noky. The 26-year-old from Derby is 25/1 to add the Big Brother title to her CV. | ITV