Injury troubles continue to be an issue for the Parkhead boss ahead of the clash with their German visitors in the second round of group-stage fixtures.
Another defeat would leave Postecoglou and his side with a really difficult task of overhauling either Leverkusen or Real Betis, who defeated the Hoops in Seville a couple of weeks ago, while a positive result would be vital in getting optimism back among the support after failure to win three of their last four league meetings.
Unfortunately, there are a number of players the Aussie is unable to call on, including summer signings Kyogo Furuhashi, Josip Juranovic and Giorgos Giakoumakis, with the latter yet to make his debut following his move from VVV-Venlo.
Captain Callum McGregor remains a significant doubt for the match, though his boss refused to rule him out of contention.
1. GK - Joe Hart
The former England No.1 is certain to start in goal. Photo: Ross MacDonald - SNS Group
2. DR - Anthony Ralston
The right-back’s form has tailed off a little from the start of the campaign, but he’ll play with limited alternatives. Photo: Ross MacDonald - SNS Group
3. DL - Adam Montgomery
It’s between the youngster and summer signing Liam Scales, but Montgomery has been trusted more so far this season. Photo: Ross MacDonald - SNS Group
4. DC - Cameron Carter-Vickers
The Tottenham loanee is unlikely to drop out. Photo: Craig Williamson - SNS Group