It’s said that all political careers end in failure and it’s certainly true that, while it’s being ousted by your party or being turfed out by the electorate, most Prime Ministers don’t leave the job of their own accord.
Currently Sir Keir Starmer is battling for control of his party a mere 18 months after a spectacular election triumph.
The intervening period has seen a succession of bad news stories for the Premier, along with cabinet scandals and embarrassing u-turns - including on an income tax rise at the last budget.
And now there is talk of open rebellion among Labour MPs following the scandal linking former British Ambassador to the United States Lord Mandelson to financier sex offender Jeffrey Epstein.
It’s led to much speculation over who will succeed him when he eventually stands aside - or is forcibly removed from office.
Here are the 11 leading candidates according to the bookies.
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1. Angela Rayner - 9/4
Angela Rayner, the former Deputy Prime Minister and Secretary of State for Housing, Communities and Local Government, lost her place in cabinet after she breached the ministerial code by underpaying stamp duty on a property in Hove. The bookies don't think her political career is finished yet though - she's the clear 6/4 favourite to take over as Labour leader. | Getty Images for SXSW London
2. Wes Streeting - 11/4
Health Secretary Wes Streeting has previously insisted he is "not challenging the Prime Minister", despite a briefing war where some close to Keir Starmer said he was after the top job. He's failed to rule out any future challenge though, and seems to harbour ambitions of leading the country. He's the 11/4 second favourite to take over from Sir Keir. | Getty Images
3. Shabana Mahmood - 8/1
Current Home Secretary Shabana Mahmood has impressed since taking on her role last September. She's 8/1 to become Labour Leader. | POOL/AFP via Getty Images
4. Andy Burnham - 9/1
Mayor of Greater Manchester Andy Burnham is a hugely popular figure with both Labour MPs and voters. He's another potential candidate who has refused to rule out standing in any leadership challenge. The one (fairly large) problem is that he's not an MP so would need to contest and win a byelection first - something that he was recently blocked from doing by the party's NEC. That's perhaps the only reason why his odds on becoming next Labour leader are as long as 9/1. | Getty Images